SHIFTING BEACH WRACK COMPOSITION IN THE SW BALTIC SEA AND ITS EFFECT ON BEACH USE



Doxazosin, a Classic Alpha 1-Adrenoceptor Antagonist, Overcomes Osimertinib Resistance in Cancer Cells via the Upregulation of Autophagy as Drug Repurposing

Osimertinib, which is a third-generation epidermal growth factor receptor tyrosine kinase inhibitor, is an important anticancer drug because of its high efficacy and excellent safety profile.However, resistance against osimertinib is inevitable; therefore, therapeutic strategies to overcome the resistance are needed.Doxazosin, a classic quinazoline

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TIA-1 Self-Multimerization, Phase Separation, and Recruitment into Stress Granules Are Dynamically Regulated by Zn2+

Summary: Stress granules are non-membranous structures that transiently form in the cytoplasm during cellular stress, where they promote translational repression of non-essential RNAs and modulate cell signaling by sequestering key signal transduction proteins.These and other functions of stress granules facilitate an adaptive cellular response to

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